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4.3 Mitophagy and metabolic-associated fatty liver diseases Metabolic associated fatty liver disease (MAFLD) refers to a series of diseases caused by multi-systemic metabolic dysfunction resulting in chronic liver damage, including hepatic steatosis, NAFLD, hepatic fibrosis, liver cirrhosis, hepatocellular carcinoma, and others ( In vitro , CP upregulates the protein levels of PGC-1, PPAR, PINK1, Parkin, ATG7, and LC3I/II in free FA (FFA)-induced NAFLD cell models, activates the PINK1-Parkin signaling pathway to promote mitophagy in liver cells, and inhibits FFA-induced OS and lipid accumulation

doi:10.1007/s10541-005-0248-3 13

Zhang Y, Li X, Li S, Zhou Y, Zhang T, Sun L

This enzyme also helps renew and strengthen the gut lining

Some particles may enter normal myometrial tissue, causing transient lack of oxygen, but dormant vessels are then recruited to keep normal uterus alive

Most daily medications are completely compatible with glutathione