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One important unresolved issue is the limited evidence regarding concomitant use of SGLT2 inhibitors and GLP-1 receptor agonists, a gap also acknowledged in European Society of Cardiology guidelines and Current guidelines prioritize SGLT2 inhibitors in patients with T2DM who have HF, chronic kidney disease, or elevated cardiovascular risk, while GLP-1 receptor agonists are emphasized for patients with obesity or established atherosclerotic cardiovascular disease [7]
While the exact endpoints of lifestyle interventions may not be easily achievable and are not solely focused on glycemic control, a suggested target is at least a 7% weight loss, presumed to improve metabolic markers such as HbA1c and C-peptide levels (97), and may help reduce the risk of microvascular complications (98)
10.1046/j.1365-2249.2002.01873.x 25
Patients should be cautious
check your specific state/plan More rollbacks possible: Following BCBS Michigan and Massachusetts cuts, some Anthem affiliates may tighten coverage For Medicare and self-pay updates: Medicare Coverage Guide | Wegovy Cost Guide ANTHEM & GLP-1 MEDICATIONS Frequently Asked Questions It depends on your specific plan
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