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Revised: May 2025 Instructions for Use TOUJEO U-300 Max SoloStar [too-JAY-oh] (insulin glargine) injection, for subcutaneous use 300 units/mL (U-300) 3 mL single-patient-use prefilled pen Read this first Do not share your TOUJEO Max SoloStar pen with other people, even if the needle has been changed

That same mechanism explains why stomach-related symptoms are among the most common complaints, particularly after starting treatment or increasing the dose

In PCOS, it improves insulin sensitivity, supports ovulatory function, modulates hepatic and ovarian gene expression, and influences gut microbiota

Additional tests may include full blood count (to check for macrocytic anaemia), methylmalonic acid and homocysteine levels (which rise in B12 deficiency), and tests for intrinsic factor antibodies if pernicious anaemia is suspected