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Importantly, however, all first- and second-generation GLP-1R agonists are still accompanied by a high incidence of illness-like behaviors as a principal side effect that include nausea and vomiting (3436)

doi: 10.1038/sj.bjc.6603291 138 BucheitADDaviesMA

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Age-related Atrophy of the Stomach Lining : As people age, the stomach lining may atrophy, leading to reduced production of hydrochloric acid and intrinsic factors, which are necessary for the absorption of vitamin B12