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The relationship between glutathione depletion and chronic disease, aging, and immune dysfunction is well-established
The peptide reduced COX-2 gene expression and myeloperoxidase activity in various inflammation models[11]
Maintaining adequate intracellular glutathione concentrations is therefore a non-negotiable requirement for cellular survival, immune regulation, and systemic health
However, the most important advantage is the very safe profile of BPC (the lethal dose (LD1) could be not achieved) (Seiwerth et al., 2018), emphasized in terms of its physiological role (assessed using in situ hybridization and immunostaining for BPC 157 in the human gastrointestinal mucosa, lung bronchial epithelium, the epidermal layer of the skin, and kidney glomeruli) (Seiwerth et al., 2018)
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