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The pharmacovigilance data revealed a significantly elevated incidence of adverse reactions in the metformin monotherapy cohort compared to the combination therapy group

Trimethylamine/Trimethylamine-N-Oxide as a key between diet and cardiovascular diseases

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Purpose-built for physicians GLP-1s lower BMI, preserve kidney function for adults with diabetes post-kidney transplant Key takeaways: Adults with diabetes who underwent kidney transplantation had greater reductions in BMI and body weight if they used a GLP-1

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In LPS-treated BV2 cells and rat primary microglia, UA inhibited the production of pro-inflammatory cytokines (e.g., NO, TNF-, and PGE2) to shield dopaminergic neurons from the toxic effects of activated microglia