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Maintenance dosing after achieving weight loss often allows reduction to 1.8-2.0mg weekly while sustaining results, providing cost savings and better tolerability for long-term use

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Least-squares mean percentage changes in body weight at week 48 were 8.7% (1 mg), 17.1% (4 mg), 22.8% (8 mg), and 24.2% (12 mg), compared with 2.1% in the placebo arm