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For example, if a certain substance is known to greatly slow down one of these enzymes, then any drug broken down by that enzyme will be present in the bloodstream in far higher amounts, leading to overdose

The experiments were performed according to the criteria of the new investigational drug application

in addition, chronic accumulation of such metals is known to increase the risk for neurodegenerative disorders, particularly of AD and PD

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In peptide and protein analysis, mass spectrometry is often paired with chromatographic methods to improve the specificity of analytical characterization [11], [13]