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Two to three hours of recreational physical activity each week may reduce the risk of cholecystectomy by about 20% (Pak 2016)

Metformin, a prescription diabetes drug in the sulfonylureas class, is typically the first-line treatment for Type 2 diabetics and has also been linked to weight loss, though it is not approved for it

Take home: the biology is interesting and the animal data are encouraging, but the clinical evidence is lacking

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Understanding gallstones and weight loss UK prevalence and statistics Gallstones are remarkably common in the UK, affecting approximately 10-15% of adults 2