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This suggests that ferroptosis, in conjunction with pyroptosis ( via NLRP3), may regulate atherosclerosis progression, offering insights into potential therapeutic targets for CAD ( 4.1.4 Non-coding RNAs as biomarkers for ferroptosis in CAD Beyond protein-based biomarkers, non-coding RNAs have emerged as ferroptosis biomarkers relevant to CAD

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Its level decreases with age (especially from the age of 45-50) and as the body's defence needs increase (immunity, liver detoxification, antioxidant defences...)