Results VRK2-deficient PC cells are vulnerable to GSH inhibition To investigate the impact of VRK2 on metabolic reprogramming, we treated VRK2-wild-type (VRK2-WT) and VRK2-knockout (VRK2-KO) CFPAC-1 cell lines with 281 metabolism compounds (Supplementary Table1)
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In addition, glutamine can support nucleotide synthesis via other pathways
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