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IGF-1 is part of a wide network of growth factors, receptors and binding proteins involved in mediating cellular proliferation, differentiation and apoptosis

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Chondrocyte Isolation and Culture Rabbit articular chondrocytes were collected from the knee cartilage of 12-week-old New Zealand female white rabbits

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however, the ability of this population of NPCs to proliferate and differentiate, particularly during the critical middle age period, is reliant on NRF2 similar to their SVZ counterparts