Melbourne Bariatric and Endoscopic Surgeon Dr Jason Winnett says, The treatment of obesity is not like taking paracetamol to treat a cold, or an infection where you take antibiotics and youre done
In the pivotal SURPASS trials evaluating tirzepatide for type 2 diabetes, nausea occurred in 1222% of patients depending on the dose (5 mg, 10 mg, or 15 mg weekly), compared to approximately 58% with placebo
It has been proposed that weight loss associated with GLP-1 agonist use may lead to better detection of breast lumps but evidence to support this association of weight loss and detection is lacking. The researchers also note that findings from the largest randomised trial of liraglutide the LEADER trial [3] , published in June 2016 did not indicate an elevated risk of breast cancer associated with the drug
10.1007/s10552-010-9725-0 39 KawanoY.NagataM.KohnoT.IchimiyaA.IwakiriT.OkumuraM.et al (2012)
doi: 10.1016/j.focha.2025.100919 Summary Keywords alleviating mechanism, gut microbiota, health benefits, live biotherapeutics, next generation probiotics, probiotics Citation El-Saadony MT, Saad AM, Sitohy M, Alkafaas SS, Dladla M, Ghosh S, Mohammed DM, Ibrahim EH, Fahmy MA, Elkelish A, AbuQamar SF and El-Tarabily KA (2026) Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review
for the cis isomer (synperiplanar conformation), and for the trans isomer (antiperiplanar conformation)
