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Deficiency causes megaloblastic anemia abnormally large, dysfunctional red cells that impair oxygen delivery, producing fatigue, shortness of breath, and pallor

However, it may have some protective effects against skin aging and may help reduce freckles and age spots to some extent (1)

Sheehan OC, Haley WE, Howard VJ, Huang J, Rhodes JD, Roth DL

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