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All findings are from short-duration preclinical models only

TRIUMPH-4: Efficacy at 68 weeks TRIUMPH-4 (ClinicalTrials.gov identifier NCT05931367) enrolled 445 adults with obesity or overweight plus symptomatic knee osteoarthritis and no type 2 diabetes

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This classification means: BPC-157 cannot be legally compounded by 503A or 503B pharmacies for human use The FDA identified concerns about immunogenicity (potential immune reactions) Peptide-related impurities in manufacturing pose risks Insufficient safety data exists to establish its safe for humans The practical impact: any BPC-157 available in the US today comes from either overseas suppliers or domestic gray-market sources operating outside FDA oversight

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