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A tumours metabolic requirements and their regulation can be changed upon cell adaptation to in vitro culture conditions, where the concentrations of glucose and glutamine are significantly higher than physiological, whereas other components are quite often missing

IUBMB Life 75:811829

Nature 464 , 783U163 (2010)

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201,411,438,456 Integration of genetics into hyperuricemia research offers opportunities for advancing personalized medical approaches and improving patient outcomes