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It co-activates GLP-1 and GIP receptors, and the research interest lies in how those signals combine

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Save Dihexa is an angiotensin-IV-derived oligopeptide marketed as a research nootropic, and its honest safety picture starts with an absence: there are no published human clinical trials of Dihexa, and therefore no human safety, toxicology, or pharmacokinetic data of any kind

doi: 10.1507/endocrj.48.63 51 YasudaTOkamotoYHamadaNMiyashitaKTakaharaMSakamotoFet al

The observed reduction in -amyloid levels in animals supplemented with high doses of paraxanthine and caffeine offers further mechanistic insights into their cognitive benefits