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IV delivery puts the vitamin directly into the blood

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However, according to recent studies, if renal tubular epithelial cells are poorly repaired, damaged renal tubular epithelial cells will produce and secrete profibrotic factors, leading to proximal tubular atrophy and renal interstitial fibrosis [12, 13]

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Furthermore, copper ions can interact with oxygen by catalyzing Haber-Weiss and/or Fenton reactions