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- when there is risk of torsades de pointes, for example in patients with prolonged QT, concomitant administration of other medications that produce torsades de pointes (amiodarone, quinidine, bepridil, IV erythromycin, halofrantine, pentamidine, sparfloxacin, sultopride, vincamine, betrilio, disopyramide, sotalol, etc)

It is intended exclusively for scientific research conducted by qualified personnel in certified facilities.

Clinical trials show retatrutide can reduce body weight by up to 24% after 48 weeks, significantly outperforming many current obesity treatments

They produce NPY and AgRP, which are the initial targets of leptin action

PMC 5788147