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As of 2025, retatrutide has not received MHRA or EMA marketing authorisation in the UK and remains in Phase 3 clinical trials

doi: 10.3390/medicina57070669

Hydration Dehydration can make you feel hungry

Retatrutide is a synthetic peptide drug designed to mimic and activate three natural hormone receptors: GLP-1, GIP, and glucagon

In rare cases, it may lead to more serious effects like gallbladder issues, which is why medical supervision is important

Your first point of contact for any concerns about your trial medication should be your trial team , who are best placed to assess whether symptoms may be related to the investigational medicine and to advise on next steps