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Being on any combination therapy early in the disease is associated with enduring advantages, sometimes termed "legacy effects," in which benefits lag behind for a while [39], [41]

Helps brighten dark spots and uneven skin tone

In dermatology, tranexamic acid has gained attention because it appears to affect pigmentation pathways involved in melasma

[150] High costs of Ozempic prompted some insurance companies to investigate and refuse to cover individuals with what the companies considered was insufficient evidence to support a diabetes diagnosis, alleging off-label prescribing for weight loss