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Requests to access the datasets should be directed to Author contributions All authors contributed to the article according to the ICJME requirements for co-authorship

Results from 1 578 482 adults diagnosed during 20002014 in 59 countries (CONCORD-3)

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The precise role of the GIPR in the metabolic profile of multi-agonist compounds remains an active scientific discussion, with debate ongoing about the optimal degree of GIPR activation versus partial modulation for maximal metabolic research outcomes