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This page is an educational overview of scientific literature and is not medical advice, not a recommendation, and not a suggestion to use, buy, or admini Research-use-only educational overview

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Loren Pickart estimated toxic action starting at approximately 22,500 mg (300-fold above effective doses), though some users report mild blood pressure effects even at normal doses

Chronic conditions like pernicious anemia require lifelong monitoring and regular doses every 2-3 months