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DOI: 10.1152/ajpregu.00520.2015, Gentinetta, S., Sottotetti, F., Manuelli, M., and Cena, H

The physiological relevance of this increase in pulse rate is yet to be elucidated

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Results Emulating pivotal cardiovascular outcome trials and expanding populations To validate our analytical framework, we emulated the cardiovascular outcome trials SUSTAIN-6 and SURPASS-CVOT using three national claims databases from the USA