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Preventing and Managing Metabolic Crises A metabolic crisis happens when the body runs out of energy, leading to low blood sugar ( hypoglycemia ) and the buildup of toxins like ammonia [1] [12]

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Both the STEP1 and SURMOUNT4 trials included the availability of RDN dietary counseling and recommendations to exercise 150 min/week during the treatment period, but with notable weight regain for most participants upon GLP1 discontinuation without continued nutrition support [18, 20]

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