polaris retatrutide clinical trial done! Now onto Zep! : r/Zepbound Retatrutide – 12mg – Prime

The goal in this phase is tolerance and consistency, not maximum fat loss

This helps people with type 2 diabetes maintain better glycemic control and prevents spikes and crashes that can occur with rapid digestion

Importantly it gave Mojsov a highly sensitive means to distinguish GLP-1 (7-37) from the larger molecule GLP-1 (1-37) based on the difference in their charges (Mojsov interview

Consider waiting for retatrutide if: You have severe obesity (BMI 40) and specifically need the difference between 15% and 28%+ weight loss a gap that matters clinically when 15% still leaves you in a high-risk range

I also cant talk about GLP-1s without acknowledging this truth: Access to obesity treatment is deeply unequal

Bakris GL, Agarwal R, Anker SD, Pitt B, Ruilope LM, Rossing P, et al