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The dense, heavily branched nature of mucins helps block diffusion by creating a mesh with very fine pores (Cone, 2009
The expression of HGF and c-MET mRNA as well as the levels of c-MET and p-c-MET protein were below detection limit in T-269 (Fig
Conclusion: Combining nasal drug delivery with natural products is a promising strategy for treating CNS, nasal, and chronic diseases, potentially improving clinical efficacy and expanding therapeutic options