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Shungus next steps revealed just how important small pilot studies funded by organizations like the Solve ME/CFS Initiative (SMCI), the Open Medicine Foundation and the Simmaron Research Foundation can be

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The compound operates through a unique triple mechanism: inhibiting the reuptake of norepinephrine (NET), dopamine (DAT), and serotonin (SERT) transporters with IC50 values of 1.7 nM, 65 nM, and 11 nM respectively

APC is seeking clarification on the decision-making process employed by the FDA in categorizing new substances into Category 2

doi: 10.1007/s10143-011-0320-y 105 TranTTUhlMMaJYJanssenLSriramVAulwurmSet al

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