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"This incidence was significantly higher compared to patients not on a GLP-1 RA, showing a strong link between GLP-1 RA drugs and potential aspiration risk under anaesthesia." The study was prompted by internal quality reviews led by Nwokolo and associate professor in the department, Dr Srikanth Sridhar, after anecdotal cases of aspiration under anaesthesia were reported by staff for patients taking this class of medications for weight loss, despite adequate fasting before the procedure

it suppresses NYP and AgRP neurons at the arcuate nucleus, thereby suppressing appetite (52, 53)

Tabe Y, Jin L, Contractor R, Gold D, Ruvolo P, Radke S, Xu Y, Tsutusmi-Ishii Y, Miyake K, Miyake N, Kondo S, Ohsaka A, Nagaoka I, Andreeff M , Konopleva M

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This process supports ATP production inside mitochondria

Primary Handling Editors: Liam Messin and Sonia Muliyil, in collaboration with the Nature Medicine team