Patients with rheumatoid arthritis who are considering semaglutide or other GLP-1 agonists must consult their rheumatologist to ensure coordination of care and to rule out contraindications
25 A pooled analysis of the findings of these two trials further showed the safety and efficacy of finerenone in a large cohort of patients with type 2 diabetes and CKD to reduce important renal and CV outcomes
This biphasic effect was also time-dependent (28)
Preclinical Studies Fourteen consecutive days of intranasal insulin reduced anxiety- and depressive-like behaviors in adult male rats subjected to the single prolonged stress (SPS) protocol, a standard paradigm to induce PTSD-like symptoms through sequential restraint, forced swimming, and exposure to ether anesthesia [35]
This vascular thrombo-inflammatory state not only drives local endothelial dysfunction, but also intersects with systemic metabolic regulation, creating a feedback loop that links neutrophil activation to tissue-level metabolic stress
Ozempic and similar GLP-1 receptor agonists have become popular weight loss tools, but MS patients require a more thoughtful, personalized approach to determine safety and compatibility with their neurological condition
