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We would expect this because Saxenda, another branded product of liraglutide, is marketed and approved for weight loss

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Common Side Effects Both medications cause primarily gastrointestinal effects: Saxenda common side effects: Nausea (39%) Diarrhea (21%) Constipation (19%) Vomiting (16%) Injection site reactions (14%) Headache (14%) Dyspepsia (10%) Semaglutide common side effects: Nausea (44%) Diarrhea (30%) Vomiting (24%) Constipation (24%) Abdominal pain (20%) Headache (14%) Fatigue (11%) Side Effect Comparison Table Interpreting the Numbers Semaglutide appears to have higher rates of GI side effects in clinical trials

The human mtRNAP conducts a higher efficiency of NAD + capping than the nuclear RNAP II, leading to ~15% NAD + capping of mitochondrial transcripts