An evidence level has been assigned to each risk category, based on RCT and observational data, as well as NICE/SIGN guidelines and the licensed indication for each GLP-1 RA therapy
Gut & Mucosal Defense: Studied for reinforcing gastrointestinal integrity and reducing gut inflammation
Ahmed MA, OCallaghan C, Chang ED, Jiang H, Vassilopoulos A (2020) Context-dependent roles for SIRT2 and SIRT3 in tumor development upon calorie restriction or high fat diet
& Amal, H
For instance, in 2024, Perelel launched Fertility+ Support, an antioxidant boost with acai, Acetyl-L-Carnitine, and CoQ10, to support egg health and reduce inflammation in early fertility stages
10.1146/annurev.pharmtox.40.1.389 [DOI] [PubMed] [Google Scholar] Lecoq I., Marie N., Jauzac P., Allouche S