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It is strongly recommended to avoid obtaining GLP-1 medications from unregulated online sources or med spas without proper medical oversight

doi: 10.1136/bmj.m2482 72

Most clinicians recommend focusing on regular meals, adequate protein, fibre-rich foods, and portion control

however, adding fiber too quickly without sufficient hydration may worsen constipation temporarily

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406 Therefore, endogenous GLP-1R signaling in astrocytes plays a critical role in maintaining mitochondrial homeostasis and is dependent on FGF21 to effectively regulate glucose metabolism