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Tirzepatide also showed fewer major heart events than dulaglutide, and when tirzepatide was compared directly with semaglutide, both performed similarly in protecting the heart

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Further work analyzing clinical trial data has demonstrated that these effects remain after taking into account exposure levels (i.e

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In terms of dosage, she explains that maintenance requires continued use of a clinically effective therapeutic dose, while microdosing involves lower doses than those typically prescribed for significant weight loss