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Curcumin induces stabilization of Nrf2 protein through Keap1 cysteine modification

Statins are inhibitors of HMG-CoA reductase (HMGCR) and widely administered as lipid-modulatory agents in primary and secondary prevention of cardiovascular disease (CVD)

A 10 gram pellet of cells was resuspended in 30 ml buffer T (25 mM Tris-HCl, pH 7.5, 10% glycerol, 0.5 mM EDTA, 1 mM DTT, 0.01% Igepal CA-630) containing 500 mM KCl and a cocktail of protease inhibitors (PIs) (5 g/ml each of aprotinin, chymostatin, leupeptin, and pepstatin A) and lysed with a Dounce homogenizer

Both sound beneficial until you consider they operate in every tissue

Proper storage to maintain peptide stability