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Published Phase 2 literature has reported substantial effects on body weight, hepatic fat, and glycemic endpoints in study populations with obesity and type 2 diabetes

For example, producing uniform PLGA microspheres with the correct size and drug loading can be technically challenging and expensive

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[18] [19] Understanding these reactions and how to prevent them can improve treatment adherence and comfort

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The effect varies considerably between individualssome experience mild reductions in appetite, whilst others report much more pronounced effects