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Based on its extensive biochemical mechanisms, buffered ascorbic acid may help manage a wide array of symptoms associated with complex chronic illnesses: Severe Fatigue and Post-Exertional Malaise (PEM): By acting as a mandatory cofactor for carnitine synthesis, vitamin C ensures that fatty acids can enter the mitochondria for ATP production, directly supporting cellular energy levels and helping to mitigate the deep exhaustion that follows physical or cognitive exertion