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After loading, transition to maintenance dosing of 1000 mcg every 1 to 4 weeks depending on response and follow-up testing

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[DOI] [PMC free article] [PubMed] [Google Scholar] 66.Arii J., Kawaguchi Y

FA dosage is 04 mg/d, unless otherwise stated

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Upon binding to AREs in the nucleus, NRF2 interacts with other co-activators, such as the CBP/p300 protein, forming a complex that further activates the transcription of antioxidant and detoxification genes [30]