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These highly bioactive compounds work by turning specific signaling proteins (like hormones and peptides) up or down

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Together, these findings suggest that cellular resistance to cuproptosis also depends on a hierarchically organized copper-buffering system, in which mtGSH provides rapid, dynamic metal buffering, whereas metallothioneins confer sustained high-affinity sequestration to prevent mitochondrial copper overload

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Some studies may be closed, paused, or limited to certain populations