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doi: 10.3389/fendo.2025.1586589 Received 03 March 2025 Accepted 29 April 2025 Published 21 May 2025 Volume 16 - 2025 Edited by Giacomina Brunetti, University of Bari Aldo Moro, Italy Reviewed by Nagesha Guthalu Kondegowda, City of Hope, United States Nikita Nirwan, Jamia Hamdard University, India Updates Copyright 2025 Chen, Lyu, Zhao, Han, Huang, Yang and Zhou

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The SURMOUNT-5 trial found approximately 20.2% average body-weight loss with branded tirzepatide versus 13.7% for branded semaglutide over 72 weeks

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