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Penetration through the dermal layers is limited, which means the amount of BPC-157 that actually reaches deeper tissues may be substantially lower than with injectable or oral forms

Sources conflict on the exact relationship: some describe fosgonimeton as a phosphate prodrug of Dihexa, while Athira has described a structurally distinct molecule so it is most accurate to call it the same program, structurally distinct, with conflicting public descriptions

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Second, early animal studies identified potential signals that warranted further investigation