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534 Astrocytic catabolism of catecholamines is also affected by ageing

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For non-diabetic individuals struggling with obesity, these medications can support significant weight loss , with clinical trials showing an average reduction of 10-15% of body weight while also improving metabolic health and blood sugar regulation

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If protein intake was too low, strength training was minimal, or muscle mass declined, the metabolic foundation remains fragile once medication support is removed