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Some research suggests that effects may be reversible once supplementation stops, meaning ongoing use may be necessary to maintain results

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Demian says

Genetic Factors That Influence How You Respond to Green Tea and GLP-1 The PlexusDx Precision Peptide Genetic Test analyzes GLP1R (rs6923761), and MC4R (rs17782313) variants that relate to GLP-1 and related signaling pathways

Exercise timing is relevant, as exercise itself lowers blood glucose, and combining exercise with IGF1 LR3 use may have additive effects

This work suggests that we may have overlooked a third phase, perhaps the most challenging one: maintaining the result over the long term