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Cagrilintide requires lower absolute doses (2.4 mg weekly maintenance), which means less raw compound is needed per injection

This altered gastric emptying can modify the entire digestive process, affecting how quickly food is broken down and absorbed throughout the gastrointestinal tract

The medication continues working to maintain that new set point, which is why discontinuation often leads to weight regain

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Phase 3 means larger groups, longer timeframes, and more safety data

Across all this human data, the rodent thyroid tumor signal has not emerged in people