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For individuals with obesity but no diabetes, GLP-1 therapy increased health care costs with no significant reduction in obesity-related health issues over two years

These trials have shown reductions in heart failure symptoms and physical limitations and greater improvement in exercise function and have led to growing interest in new ways to address HFpEF, a condition with limited guideline direct medication therapy compared to heart failure with reduced ejection fraction (HFrEF)

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While pharmacotherapies for treatment of obesity prior to GLP-1RAs have had limited impact on cardiovascular outcomes, bariatric surgical procedures have shown long-standing, durable outcomes [7]

Continuing and constant surveillance of pregnant women prescribed these drugs is essential to understand any potential risks associated with their use

It is a stimulant like tea, coffee or cocoa