The benefit of weight loss does not justify deteriorating mental health
Over up to seven years of follow-up, those treated with semaglutide or tirzepatide had a 37% lower risk of developing dementia (hazard ratio [HR] 0.63, 95% CI 0.500.81), a 19% lower risk of stroke (HR 0.81, 95% CI 0.700.93), and a 30% lower risk of all-cause mortality (HR 0.70, 95% CI 0.630.78), compared to those on other antidiabetic drugs
How GLP-1 drugs might affect the skin If you're dealing with unwanted skin changes due to extreme weight loss from a GLP-1, you're not alone
doi: 10.1038/ng.2776 82 BaraghithySSmoumRDroriAHadarRGammalAHirschSet al
Both of these were taken from pure fat burners to supplements that were more like "light energy supplements", and the removal of higenamine was definitely part of those reformulations
GSH metabolism promotes the proliferation of HG cells Stem cells change metabolism during homeostasis and proliferation [37], and glutamine metabolism is constantly shifted among HFSCs during their exit from their bulge niche to produce outer root sheaths during anagen progression, as well as the return of a subset of outer root sheath progeny to the bulge niche to restore the stem cell state to adapt to and regain reversibility of the HFSC fate during catagen [5]
