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This reaction provides a sensitive and relatively specific method for detecting thiol groups in various biological samples
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PubMed , Cell Death & Disease , vol
There are three amino acids in Glutathione: glycine, glutamic acid, and cysteine
If not reduced by the GPX system, lipid hydroperoxides can accumulate and decompose, yielding lipid peroxyl radicals (LOO*) and/or lipid alkoxyl radicals (LO*), which can amplify lipid peroxidation with the formation of additional lipid hydroperoxides [59]
When the bodys antioxidant defenses, such as Glutathione, are depleted, oxidative damage can increase, and cells can become less responsive to insulin
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