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How Mitochondria Produce ATP Mitochondrial Disease Is Not the Same as Acquired Mitochondrial Dysfunction Primary mitochondrial disease Primary mitochondrial diseases are generally caused by pathogenic variants in mitochondrial DNA or nuclear genes that control mitochondrial structure and function

95% CI 0.690.84) and without established disease but multiple risk factors (HR 0.84

For detailed protocols, you would need to consult specialized scientific literature

Patients should also be informed about potential side effects and provided with guidance on how to mitigate these

NEJM 375(26):2570-2581