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This emphasis on long-term behavioral and psychological support is further underscored by a recent BMJ systematic review and meta-analysis showing rapid and clinically meaningful weight regain after discontinuation of weight-management medications, with regain occurring faster than after behavioral weight-management programmes [97]

FDA Approval for Non-Diabetics: Currently, the FDA has not approved Ozempic for obesity, although some healthcare providers may prescribe it off-label for this use

Both types of exercise are important

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Fifth, although adverse events and discontinuation rates were extracted, these outcomes were not formally analyzed because of substantial heterogeneity in reporting across trials, including differences in definitions, timepoints, and outcome structure (event-based vs patient-based)

that coverage also requires prior authorization