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(44-46) As a word of caution, in some individuals, glutamine can lead to the production of excess glutamate (this can act as an excitatory neurotransmitter and lead to anxiety, insomnia, and headaches)

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However, people with low energy or less mobility may benefit more from larger MIC b12 doses

In mammals, cobalamin is a cofactor for only two enzymes, methionine synthase and L-methylmalonyl-coenzyme A mutase (2)

Modest weight loss often produces substantial symptom improvement independent of other interventions